The mediating effect of catastrophizing was responsible for over 30 % of the total effect seen in correlation between pain and disability experienced by patients with CTS. While the effect of magnification sub-score was borderline and could probably be ignored in clinical context, domain of helplessness reached the effect size of almost 40 %. The results suggest that catastrophizing should be considered when treating or rehabilitating people with CTS. Catastrophizing may play a significant role in the development of pain-related disability.
Sainio et al. (Thu,) studied this question.