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March 7, 2026

Evaluation of the association between prostate-specific antigen density and systematic prostate biopsy pathological results.

Coşkun Bostancı Kazım Erdem

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Key Points

This research aims to evaluate the role of prostate-specific antigen density in predicting prostate cancer aggressiveness and biopsy outcomes.
Utilized prostate-specific antigen density as a marker in assessing biopsy results.
Analyzed the correlation between PSA density and prostate cancer aggressiveness.
Considered the effectiveness of PSA density in clinical decision-making for diagnosis.
PSA density demonstrated a higher diagnostic accuracy compared to traditional PSA.
The incorporation of PSA density improved the likelihood of identifying clinically significant prostate cancer.

Implication

Evaluation shows improved detection of significant prostate cancer with PSA density, suggesting enhanced decision-making in clinical settings.

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Cite This Study

Bostancı et al. (2026) studied this question.

synapsesocial.com/papers/69af955970916d39fea4cd9c https://doi.org/10.1177/03915603261426555

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Association between PSA density and pathologically significant prostate cancer: The impact of prostate volumePrognostic Study · 2020 · 108 citations
2PROSTATE SPECIFIC ANTIGEN DENSITY AS A PREDICTOR FOR PROSTATE CANCER IN CASES WITH PROSTATE SPECIFIC ANTIGEN LEVELS GREATER THAN 4NG/ML2025
3Integrating PSA Change with PSA Density Enhances Diagnostic Accuracy and Helps Avoid Unnecessary Prostate Biopsies2025 · 8 citations
4Utility of prostate-specific antigen density and its correlation with Gleason grade groups: a hospital-based cross-sectional study among patients with prostate-related urinary symptoms at Bugando Medical Centre, Mwanza, TanzaniaCross-Sectional Study · 2026
5PSA Density and PI-RADS in the Detection of Clinically Significant Prostate Cancer: A Radiological Literature ReviewNarrative Review · 2024

Precision in prostate cancer detection: integrating prostate-specific antigen density (PSAD) and the Prostate Imaging Reporting and Data System (PI-RADS) to provide additional risk stratification for a more accurate diagnostic decision2024
Predicting Prostate Cancer in PI-RADS 1–2 Lesions: The Role of Prostate-Specific Antigen Density, Digital Rectal Examination, and Family History2025
The Application of Biopsy Density in Transperineal Templated-Guided Biopsy Patients With PI-RADS<32022

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