Research unveils a manganese-doped platform that enhances immunity in liver cancer, suggesting new therapeutic approaches.
Single-Metal-Doped Nanoplatforms In their Research Article (10.1002/adfm.202520463), Malcolm Xing, Shiming Yang, and co-workers present manganese-doped metal–organic frameworks that induce ferroptosis-mediated release of endogenous mitochondrial DNA, thereby synergistically activating the manganese-specific cGAS-STING signaling pathway to promote dendritic cell maturation and remodel the immunosuppressive tumor microenvironment in liver cancer.
No takes yet. Share an insight, caveat, or question.
Zhang et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: