Multimodal magnetic resonance imaging outcomes of transcranial direct current stimulation in psychiatric and neurological disorders: a systematic review

Mariana Pita; Pedro H. R. Silva; Beatriz Cavendish; Tamires Zanão; Laís B. Razza; Andre R. Brunoni

doi:10.1080/17434440.2026.2641166

March 9, 2026Expert Review of Medical Devices

Multimodal magnetic resonance imaging outcomes of transcranial direct current stimulation in psychiatric and neurological disorders: a systematic review

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Key Points

The aim is to address the current limitations in understanding the mechanisms and biomarkers associated with tDCS through MRI.
Conducted a systematic review of existing trials on tDCS and MRI outcomes.
Analyzed the heterogeneity in MRI methodologies used in tDCS studies.
Identified key areas for standardization in MRI acquisition and analysis.
Found significant variability in MRI protocols across tDCS studies.
Highlighted that standardizing methods is crucial for reproducible outcomes.
Pointed out that improving protocols can facilitate the establishment of reliable biomarkers.

Implication

A systematic review highlights the need for standardized MRI methods to establish tDCS biomarkers in various disorders, suggesting improved research reproducibility.

Discussion

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Cite This Study

Pita et al. (2026) studied this question.

synapsesocial.com/papers/69b2579096eeacc4fcec64c1 https://doi.org/10.1080/17434440.2026.2641166

View Full Paper

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Multimodal magnetic resonance imaging outcomes of transcranial direct current stimulation in psychiatric and neurological disorders: a systematic review

Key Points

Implication

Discussion

Cite This Study

Multimodal magnetic resonance imaging outcomes of transcranial direct current stimulation in psychiatric and neurological disorders: a systematic review

Key Points

Implication

Discussion

Cite This Study

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