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October 1, 2025Indian Journal of CancerOpen Access

Effectiveness of interstitial brachytherapy in extremity sarcoma—treatment outcomes and current concepts

Amar M. Kamat Anto Gopurathingal Pramod S. Chinder Suraj Hindiskere MS Belliappa

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Key Points

The aim is to evaluate the effectiveness of interstitial brachytherapy in treating extremity sarcoma.
Conducted a case series of patients with extremity sarcoma treated with interstitial brachytherapy (ISBT)
Included cases treated with ISBT combined with external beam radiotherapy (EBRT)
Utilized an Iridium 192-based high-dose rate (HDR) system for treatment.
Achieved excellent local control of the sarcoma
Observed long-term survival rates among treated patients
Documented acceptable levels of skin toxicities and wound complications.

Implication

Case series shows excellent local control and long-term survival in extremity sarcoma, indicating effective treatment options.

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Cite This Study

Kamat et al. (2025) studied this question.

synapsesocial.com/papers/69b2579096eeacc4fcec6531 https://doi.org/10.4103/ijc.ijc_796_23

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Interstitial brachytherapy in soft tissue sarcoma: a 5 years institutional experience with Cobalt 60- based high-dose-rate brachytherapy systemOriginal Research · 2018 · 15 citations
2Intraoperative radiotherapy (IORT) as a boost in soft tissue sarcomas of the extremity: long-term results of a retrospective cohortCohort Study · 2026
3Evidence and clinical outcomes of adult soft tissue sarcomas of the extremities treated with adjuvant high-dose-rate brachytherapy – a literature reviewreview · 2014 · 9 citations
4High-Dose-Rate Brachytherapy for Treatment of Facial Skin Cancers: Local Control, Toxicity, and Quality of Life in 67 Patients2024 · 4 citations
5Durable local control following salvage interstitial brachytherapy for anorectal cancer pelvic recurrence: a retrospective seriesCohort Study · 2026

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Factors Influencing Long-Term Local Recurrence, Distant Metastasis, and Survival in Patients with Soft Tissue Sarcoma of the Extremities Treated with Radiotherapy2024

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