A Mechanochemical Construction of C-P Bonds through Radical-Radical Coupling

Ruizhi Sun; Juxin Jiang; Wenhao Li; Zengdian Zhao; Dong Liu; Hui Liu; Lu Zhang

doi:10.1039/d6cc00876c

January 1, 2026Chemical Communications

A Mechanochemical Construction of C-P Bonds through Radical-Radical Coupling

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Key Points

The research aims to develop a mechanochemical method to synthesize aryl phosphorus compounds efficiently.
Developed a magnesium-mediated protocol for synthesis.
Performed synthesis at room temperature.
Utilized radical-radical coupling techniques.
Successfully synthesized ary phosphine oxides.
Demonstrated efficiency of the mechanochemical method at room temperature.

Implication

A mechanochemical method synthesizes C-P bonds in aryl phosphorus compounds, suggesting a new approach for organic synthesis.

Abstract

Aryl Phosphorus compounds are indispensable motifs in organic synthesis, medicinal, and materials chemistry. Herein, we report a robust magnesium-mediated mechanochemical protocol for the room-temperature synthesis of ary phosphine oxides through...

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Cite This Study

Sun et al. (2026) studied this question.

synapsesocial.com/papers/69b257bf96eeacc4fcec6a54 https://doi.org/10.1039/d6cc00876c

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A Mechanochemical Construction of C-P Bonds through Radical-Radical Coupling

Key Points

Implication

Abstract

Discussion

Cite This Study

A Mechanochemical Construction of C-P Bonds through Radical-Radical Coupling

Key Points

Implication

Abstract

Discussion

Cite This Study

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