A case report reveals metastatic prostate cancer recurrence in a biopsy tract, suggesting improved detection with PSMA PET/CT.
Background Metastatic prostate cancer tumor seeding within a percutaneous biopsy tract is rare. While reports of tumor seeding following perineal and transrectal prostate biopsies exist, no cases of prostate cancer tumor seeding along a metastatic percutaneous bone biopsy tract detected by prostate specific membrane antigen (PSMA) positron emission tomography (PET)/computed tomography (CT) have been reported. Case Presentation We describe a rare case of intramuscular and subcutaneous prostate cancer recurrence along and adjacent to the site of a previous percutaneous metastatic rib biopsy tract. The role of PSMA PET/CT in the early detection of such cases is highlighted. In this case, PSMA PET played a crucial role in achieving both early diagnosis and early targeted management, optimizing the oncological outcome for the patient. Conclusion We hope to increase awareness of this rare presentation and emphasize the need for consensus on management approaches when encountering similar cases of prostate cancer tumor seeding in the future.
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Neerhut et al. (2026) studied this question.
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