Meta-analysis shows doxycycline reduces STIs in MSM and TGW, indicating it as a valuable prevention tool.
RCT and non-RCT data demonstrated the effectiveness of doxy PrEP and doxy PEP in reducing STIs among MSM/TGW. Integrating doxy PrEP or doxy PEP as a biomedical tool into STI prevention strategies should be considered.
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Zhao et al. (2026) studied this question.
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