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March 12, 2026Journal of Translational Medicine2 citationsOpen Access

Noble gases xenon and argon: from cellular signalling mechanisms to organoprotection and clinical applications

QCQian ChenSZShifan ZhuMWMei Wu

Key Points

  • The aim is to explore the roles of noble gases xenon and argon in cellular signaling and their potential clinical applications.
  • Review of current literature on xenon and argon in medical applications.
  • Analysis of the mechanisms of cellular signaling by these noble gases.
  • Discussion on delivery systems and dosing strategies for clinical use.
  • Xenon and argon demonstrate significant organoprotection in perioperative settings.
  • Identification of gaps in standardized delivery methods and optimized dosing for clinical applications.

Abstract

Xe and Ar represent novel biologically active gases with the potential to provide promising therapies in perioperative and clinical care medicine. Overcoming current limitations, such as a lack of standardized delivery systems and optimized dosing strategies, is key to uncovering their clinical application.

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Cite This Study

Chen et al. (2026) studied this question.

synapsesocial.com/papers/69b2582a96eeacc4fcec7855https://doi.org/10.1186/s12967-026-07944-2
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