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March 12, 2026BJU International2 citationsOpen Access

Transrectal vs transperineal prostate biopsy: a systematic review and meta‐analysis

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GCGavin CalpinCHCian HehirMAMariyah Ihab Alzayer

Key Points

  • This research aims to compare the safety and effectiveness of transrectal and transperineal prostate biopsy techniques in detecting prostate cancer.
  • Conducted a systematic review and meta-analysis of existing literature
  • Compared infection and sepsis rates between LATP biopsy and TRUS biopsy
  • Analyzed cancer detection rates and clinical significance based on Gleason grades
  • LATP biopsy shows lower rates of infection and sepsis compared to TRUS biopsy
  • Higher incidence of overall prostate cancer detection with LATP biopsy
  • Clinically significant prostate cancer (Gleason Grade Group 2-5) detected more frequently with LATP biopsy

Abstract

The LATP biopsy is associated with lower rates of infection and sepsis compared to TRUS biopsy. The LATP biopsy also detects a higher overall incidence of prostate cancer and clinically significant prostate cancer (Gleason Grade Group 2-5).

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Cite This Study

Calpin et al. (2026) studied this question.

synapsesocial.com/papers/69b2588496eeacc4fcec84eehttps://doi.org/10.1111/bju.70204
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