Transperineal Versus Transrectal Biopsy for Prostate Cancer Diagnosis: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Key Points

• The study aims to compare the effectiveness and safety of transperineal biopsy versus transrectal biopsy for diagnosing prostate cancer.
• Conducted a systematic review of randomized controlled trials
• Analyzed infection rates, discomfort, and detection rates
• Compared outcomes between transperineal biopsy (TP-Bx) and transrectal biopsy (TR-Bx)
• TP-Bx showed lower infection rates without the need for antibiotics
• Detection rates for prostate cancer were equivalent between TP-Bx and TR-Bx
• TP-Bx resulted in minimal increases in discomfort and procedure time