Cost Effectiveness of Transrectal and Transperineal Prostate biopsy: Analysis from the ProBE-PC Randomized Study

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Key Points

This analysis evaluates the cost implications of transrectal versus transperineal prostate biopsy based on clinical outcomes.
718 men completed TR-Bx or TP-Bx procedures under local anesthesia.
Cost analysis used modified time-driven activity-based costing including all complication costs.
Costs for supplies, personnel, and complications were considered in the overall cost calculation.
TP-Bx incurred a significantly higher procedural cost ($323.78) compared to TR-Bx ($124.28, p < 0.001).
The cost of complications per biopsy was not significantly different between TP-Bx ($11.13) and TR-Bx ($19.26, p=0.54).
The total median cost, including complications, was significantly higher for TP-Bx ($326.78) compared to TR-Bx ($126.29, p < 0.005).

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Randomized trial analyzes cost differences in prostate biopsy techniques, suggesting implications for healthcare choices.

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Gaba et al. (2026) studied this question.

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