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Research demonstrates the role of Wnt/beta-catenin pathway in hyperalgesia and anxiety-like behaviour in male rats, indicating potential therapeutic targets.
Modulating the spinal Wnt/β-catenin signalling pathway may be pivotal for elucidating the mechanisms underlying hyperalgesia and anxiety-like behaviour in chronic nonspecific low back pain (CNLBP).
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Xu et al. (2026) studied this question.
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