This translational study examines FKBP5's impact on stroke outcomes in mice and humans, suggesting potential therapeutic insights.
Loss of Fkbp5 leads to improved outcome in experimental stroke. In addition, the FKBP5 risk haplotype, indicative of increased FKBP5 expression, was associated with poor functional outcome following stroke.
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Liman et al. (2026) studied this question.
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