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This methodology paper describes IDIBS™, a tool assessing skin compatibility, suggesting new clinical archetypes for personalized care.
IDIBS™ (Individualized Dynamic Index of Systemic Biocompatibility for Skin) is a composite multidimensional instrument integrating nine weighted sub-indices — ICE-8™ (exposome), CINC™ (nutritional), ICRC™ (circadian), JTDA™ (neuroendocrine-adaptive), IHCP™ (hormonal), IEPA™ (epigenetic), IGSM™ (gut-microbiome), ICMC™ (cutaneous microbiome), and ICCE™ (phytochemical compatibility) — into a holistic score (0–100) mapping to four clinical archetypes (PURIFICA™, RENOVA™, ILUMINA™, ACALMA™). This methodology paper describes the architecture, weighting rationale, and proposed validation pathway of IDIBS™ within the Fitodermonutrição™ framework.
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Willer de Souza (2026) studied this question.
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