Photocatalyzed Generation of Acyl Radicals from Aryl/Alkyl Acyl Halides via Nucleophilic Substitution

Haowen Zhan; Jiansheng Chen; Yajing Luo; Yang Ke; Xinjun Tang

doi:10.1039/d6cc00687f

January 1, 2026Chemical Communications

Photocatalyzed Generation of Acyl Radicals from Aryl/Alkyl Acyl Halides via Nucleophilic Substitution

View Full Paper

Ask AI

Bookmark

Share

Key Points

This research aims to develop a nucleophilic catalytic strategy to generate acyl radicals from acyl halides using a specific catalyst.
Utilized 1methylpyridine-2(1H)-thione catalyst for photocatalysis.
Explored various aryl and alkyl acyl halides.
Employed nucleophilic substitution to form photoactive intermediates.
Successfully generated acyl radicals from diverse acyl halides.
Demonstrated the efficiency of the MPT catalyst in radical formation.

Ask about this paper

Answers are grounded in this paper and cite their sources.

Implication

Nucleophilic catalysis generates acyl radicals from acyl halides, suggesting a new synthetic approach.

Abstract

Herein, we introduce a nucleophilic catalysis strategy based on 1methylpyridine-2(1H)-thione (MPT) catalyst, which mediates the in-situ generation of photoactive intermediates from various acyl halides. This strategy enables efficient formation of...

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Zhan et al. (2026) studied this question.

synapsesocial.com/papers/69b25b2b96eeacc4fcec99ba https://doi.org/10.1039/d6cc00687f

View Full Paper

Ask AI

Bookmark

Share

Photocatalyzed Generation of Acyl Radicals from Aryl/Alkyl Acyl Halides via Nucleophilic Substitution

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Photocatalyzed Generation of Acyl Radicals from Aryl/Alkyl Acyl Halides via Nucleophilic Substitution

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading