Dedicated First-Trimester Anomaly Scan in a National Prenatal Screening Program and Timing of Diagnosis: The Prospective IMITAS Cohort Study.

Kim Bronsgeest; Eline E R Lust; L Henneman; Neeltje Crombag; Caterina M. Bilardo; Robert-Jan H Galjaard; Esther Sikkel; Nan van Geloven; A. Coumans; A. Elvan; Sander Galjaard; Attie T. J. I. Go; Elisabeth van Leeuwen; Gwendolyn T R Manten; Eva Pajkrt; M. N. Bekker; Monique C Haak

doi:10.1111/1471-0528.70192

March 10, 2026

Dedicated First-Trimester Anomaly Scan in a National Prenatal Screening Program and Timing of Diagnosis: The Prospective IMITAS Cohort Study.

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Key Points

To evaluate the impact of dedicated first-trimester anomaly scans on the detection of fetal anomalies in a national screening program.
Conducted a prospective cohort study during the first trimester of pregnancy.
Utilized dedicated first-trimester anomaly scans for detecting fetal anomalies.
Assessed timing of diagnosis and terminations of pregnancy (TOP) related to detected anomalies.
Significant increase in the detection rates of fetal anomalies through dedicated scans.
Marginal improvement in gestational age at diagnosis and TOP timelines.
Some cases required longer periods for diagnostic evaluation before conclusive outcomes.

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Implication

Prospective IMITAS cohort study shows improved anomaly detection in prenatal screening, suggesting enhanced diagnostic outcomes.

Abstract

FTAS substantially increases detection of fetal anomalies, primarily often detectable and other anomalies. Overall GA at diagnosis or TOP increased marginally, but some cases required an extended period of diagnostic evaluation.

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Cite This Study

Bronsgeest et al. (2026) studied this question.

synapsesocial.com/papers/69b25b3896eeacc4fcec9bf5 https://doi.org/10.1111/1471-0528.70192

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Dedicated First-Trimester Anomaly Scan in a National Prenatal Screening Program and Timing of Diagnosis: The Prospective IMITAS Cohort Study.

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Dedicated First-Trimester Anomaly Scan in a National Prenatal Screening Program and Timing of Diagnosis: The Prospective IMITAS Cohort Study.

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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