While parvovirus B19 is classically associated with erythema infectiosum and papular purpuric gloves and socks syndrome, multiple additional cutaneous manifestations have been reported in the literature. This paper describes a 10-year-old girl with a generalized petechial and purpuric eruption involving the trunk, extremities, and face with distinct perioral involvement. Diagnostic evaluation, including histopathology and polymerase chain reaction testing, confirmed acute parvovirus B19 infection with spontaneous resolution over several weeks. This case highlights an atypical presentation that expands the recognized dermatologic spectrum of parvovirus B19 and emphasizes the importance of maintaining diagnostic vigilance in pediatric exanthems to guide appropriate testing and avoid unnecessary interventions.
Stokes et al. (Mon,) studied this question.