Case report illustrates delayed onset of akathisia symptoms with cariprazine, emphasizing diagnostic challenges.
This case highlights the challenge of distinguishing akathisia from primary anxiety disorders, in addition to considering this diagnosis beyond the initial treatment period. Akathisia symptoms most commonly present within 4 weeks of initiation or titration of antidopaminergic treatment. However, this timeline may be delayed with cariprazine due to its pharmacokinetic and pharmacodynamic properties.
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Goodrich et al. (2026) studied this question.
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