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Comparison shows glucose levels in serum and NaF plasma are similar, indicating practical diagnostic use in outpatient settings.
In real-world outpatient settings, glucose measurement in on-site centrifuged serum with separator gel does not appear to present a clinically relevant disadvantage for diabetes mellitus screening compared to on-site uncentrifuged NaF plasma. However, neither serum nor non-acidified NaF plasma ensures complete inhibition of in vitro glycolysis and must therefore be regarded as suboptimal for definitive diagnostic purposes.
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Müller et al. (2026) studied this question.
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