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The review aims to evaluate contemporary diagnostic and treatment approaches for mild traumatic brain injury (mTBI).

March 13, 2026Brain CirculationOpen Access

Reframing the “mild” in mild traumatic brain injury: A comprehensive narrative review of diagnosis and treatment paradigms

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The review aims to evaluate contemporary diagnostic and treatment approaches for mild traumatic brain injury (mTBI).
Conducted a literature search across PubMed, Cochrane Library, EMBASE, and Web of Science from January 2018 to January 2025.
Included 183 studies: 42 systematic reviews, 58 randomized controlled trials, and 83 observational studies.
Analyzed advances in biomarker research and neuroimaging techniques, with a focus on treatment strategies.
Identified promising early intervention strategies and cognitive rehabilitation approaches.
Highlighted challenges in standardizing diagnostic definitions and treatment protocols.
Noted the need for large-scale trials to address methodological limitations and improve care access for vulnerable populations.

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This review synthesizes evidence on diagnosis and treatment of mild traumatic brain injury, highlighting implications for healthcare.

SASIDHARAN et al. (2026) studied this question.

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