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Research Paper | Synapse

March 13, 2026Alzheimer s & Dementia0 citations

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Integrating real‐world data with gold‐standard longitudinal clinical and genomic data to advance precision medicine for the Alzheimer's Disease Research Center Program and beyond: a proof‐of‐concept data platform

SBSarah BiberUniversity of Washington JCJessica E. CulhaneUniversity of Washington MPMaria G. PradoUniversity of Washington

Key Points

The central aim is to evaluate the feasibility of integrating various data types to improve Alzheimer's research.
Developed a proof-of-concept data platform.
Integrated clinical and genomic data with real-world data (RWD).
Assessed the model for scalability across Alzheimer's Disease Research Centers (ADRCs).
Demonstrated effective integration of diverse data types.
Showed potential for broader implementation of the data platform across various research settings.
Provided a scalable model for enhancing precision medicine in Alzheimer’s research.

Abstract

This POC demonstrates the feasibility of integrating clinical, genomic, and RWD across ADRCs, offering a scalable model for broader implementation.

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Cite This Study

Biber et al. (Sun,) studied this question.

synapsesocial.com/papers/69b3ab4c02a1e69014ccc1aa https://doi.org/https://doi.org/10.1002/alz.71207