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January 1, 2026Journal of Analytical Atomic Spectrometry

Enhanced ion utilization efficiency in IMS-TOFMS using a novel gate-free traveling wave ion guide

Zhekun Wang Zhongjun Zhao Zhihao He Xiaoqin Jiang Yanting Yang Jianxiong Dai Ziqiu Su Xing Guo Yixiang Duan

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Key Points

The research aims to enhance ion utilization efficiency in ion mobility spectrometry-mass spectrometry (IMS-MS).
Developed a novel gate-free traveling wave ion guide for IMS-MS.
Evaluated ion separation and detection capabilities with the new ion guide.
Conducted assessments in a metabolomics context using electrospray ionization.
Achieved significant improvements in ion detection rates.
Demonstrated enhanced resolution in ion separation.
Showed greater sensitivity compared to traditional ion guides.

Implication

Demonstrates improved ion efficiency in IMS-MS using a novel ion guide, indicating potential benefits for metabolomics.

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Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/69b3ab5e02a1e69014ccc2ed https://doi.org/10.1039/d5ja00415b

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