Key result
Untreated atrial fibrillation leads to rare embolic isolated septal MI from LAA thrombus.
Case Report (n=1)
This case highlights a rare presentation of isolated septal myocardial infarction caused by a coronary embolism from a left atrial appendage thrombus, underscoring the severe consequences of non-adherence to anticoagulation in atrial fibrillation.
Alerts to embolic septal MI risk in anticoagulant-intolerant AF; leaves open optimal prevention strategies.
We present a case of a 76‐year‐old female who experienced an isolated embolic occlusion of the septal branch, resulting in a septal myocardial infarction (MI) due to a thrombus in the left atrial appendage (LAA). The patient′s history included atrial fibrillation (AF), multiple allergies, and a self‐discontinued anticoagulation regimen. This case underscores the importance of anticoagulation therapy in AF patients and highlights the challenges of managing patients with complex medical histories and medication intolerances.
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Jano et al. (2026) conducted a case report in Atrial fibrillation with septal myocardial infarction (n=1). Untreated atrial fibrillation (discontinuation of anticoagulation) was evaluated on Development of isolated septal myocardial infarction. Untreated atrial fibrillation due to anticoagulant intolerance resulted in a rare isolated septal branch occlusion leading to a septal myocardial infarction from a left atrial appendage thrombus.
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