Base-Promoted Intermolecular Cyclization of Substituted 3-Aryl-3-chloropropenals with Tetrahydro-β-carboline: A Method for the Synthesis of Indolizino[8,7-b]indole Compounds

Q: What does this research mean for the field?

The base-promoted intermolecular cyclization of 3-aryl-3-chloropropenals with tetrahydro-β-carboline provides a practical method for synthesizing indolizino[8,7-b]indole compounds. Novelty: ClaimNovelty.METHODOLOGICAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Kai rong Chen; Miao Yang; Shuang Chen; Yuxin Gong; Junnan Xu; Mei xiang Ye; Jie Zhang; Liang Guo

doi:10.1039/d6ob00015k

January 1, 2025Organic & Biomolecular Chemistry

Base-Promoted Intermolecular Cyclization of Substituted 3-Aryl-3-chloropropenals with Tetrahydro-β-carboline: A Method for the Synthesis of Indolizino[8,7-b]indole Compounds

View Full Paper

Ask AI

Bookmark

Share

Key Points

The aim is to develop a new method for synthesizing indolizino[8,7-b]indoles using a base-promoted reaction.
Conducted an intermolecular tandem cyclization reaction.
Used 3-aryl-3-chloropropenals and tetrahydro-β-carboline as reactants.
Analyzed the reaction to determine yields and effectiveness.
Successfully synthesized indolizino[8,7-b]indole compounds.
Yielded a product with a simple and practical reaction method.

Ask about this paper

Answers are grounded in this paper and cite their sources.

Implication

Novel base-promoted cyclization synthesizes indolizino[8,7-b]indole compounds, suggesting a new method in organic chemistry.

Abstract

This paper reports a novel base-promoted intermolecular tandem cyclization reaction between 3-aryl-3-chloropropenals and tetrahydro-β-carboline. This reaction provides a simple and practical method for the synthesis of indolizino[8,7-b]indoles, yielding a...

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Chen et al. (2025) studied this question.

synapsesocial.com/papers/69b3abc502a1e69014cccf39 https://doi.org/10.1039/d6ob00015k

View Full Paper

Ask AI

Bookmark

Share

Base-Promoted Intermolecular Cyclization of Substituted 3-Aryl-3-chloropropenals with Tetrahydro-β-carboline: A Method for the Synthesis of Indolizino[8,7-b]indole Compounds

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Base-Promoted Intermolecular Cyclization of Substituted 3-Aryl-3-chloropropenals with Tetrahydro-β-carboline: A Method for the Synthesis of Indolizino[8,7-b]indole Compounds

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading