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Evaluate methodologies for assessing cost-effectiveness in Ghana's community health centres and propose a multilevel regression framework.

March 13, 2026Open Access

A Methodological Review and Multilevel Regression Analysis of Cost-Effectiveness in Ghanaian Community Health Centre Systems

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Evaluate methodologies for assessing cost-effectiveness in Ghana's community health centres and propose a multilevel regression framework.
Conducted a systematic review of published and grey literature
Applied a three-level random intercepts model to analyze cost-effectiveness
Inferred estimates using robust standard errors clustered at the district level.
Identified reliance on simple cost-per-output ratios lacking robustness
A 10% increase in operational expenditure linked to a 3.2% increase in service coverage
Highlighted the need for better models to account for district-level heterogeneity.

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Methodological review analyzes cost-effectiveness in Ghanaian health centres, suggesting robust evaluation frameworks for accurate estimates.

Asare et al. (2000) studied this question.

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Methodological review analyzes cost-effectiveness in Ghanaian health centres, suggesting robust evaluation frameworks for accurate estimates.