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March 13, 2026Journal of Cachexia Sarcopenia and Muscle0 citationsOpen Access

Associations Between Body Composition and Intratumoural Immune Cells in Patients With Uterine Cervical Cancer

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ASAlexey SurovAHAnne‐Katrin HöhnMHMattes Hinnerichs

Key Points

  • To investigate the relationship between body composition and immune cell infiltration in uterine cervical cancer.
  • Analyzed body composition parameters including myosteatosis, subcutaneous adipose tissue (SAT), and intramuscular adipose tissue (IMAT) radiodensity.
  • Assessed immune cell infiltration levels in tumor samples from patients with uterine cervical cancer.
  • Utilized statistical analyses to determine associations between body composition and immune cell presence.
  • High levels of myosteatosis were linked to lower immune cell infiltration.
  • Increased SAT and higher IMAT radiodensity were associated with reduced stromal immune cells.
  • These body composition factors may act as potential prognostic markers, aiding in patient risk assessment.

Abstract

Myosteatosis, high SAT and increased IMAT radiodensity were associated with reduced stromal and intratumoural immune cell infiltration in patients with UCC. These body composition parameters may serve as prognostic markers and should be explored in risk stratification.

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Cite This Study

Surov et al. (2026) studied this question.

synapsesocial.com/papers/69b3aca302a1e69014cce813https://doi.org/10.1002/jcsm.70241
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