What does this research mean for the field?

In patients with reduced left ventricular ejection fraction, both balloon-expandable and self-expandable TAVI improve ejection fraction, with self-expandable valves providing a haemodynamic advantage but no difference in clinical outcomes. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This study aims to compare the effectiveness of balloon versus self-expandable valves in TAVI for patients with left ventricular dysfunction.

March 13, 2026Catheterization and Cardiovascular Interventions0 citations

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Balloon Versus Self‐Expandable TAVI in Patients With Left Ventricular Dysfunction: A Real‐World Comparative Study

EDEdward DababnehInterventional Cardiology MMMaría Gabriela MattaCardiac Imaging SNSelvanayagam NiranjanGriffith University

Key Result

In patients with reduced LVEF, both balloon and self-expandable TAVI improved ejection fraction, but SEV showed better haemodynamics without differing outcomes.

Key Points

This study aims to compare the effectiveness of balloon versus self-expandable valves in TAVI for patients with left ventricular dysfunction.
Conducted a real-world comparative study
Analyzed ejection fraction and clinical outcomes in patients with reduced LVEF
Evaluated haemodynamic changes between valve platforms
TAVI leads to sustained improvement in ejection fraction regardless of valve type
Self-expandable valves show a haemodynamic benefit without significant differences in overall outcomes

Structured PICO

Does self-expandable TAVI improve ejection fraction or clinical outcomes compared to balloon-expandable TAVI in patients with reduced LVEF?

Population

Patients with reduced left ventricular ejection fraction (LVEF) undergoing transcatheter aortic valve implantation (TAVI)

Intervention

Self-expandable transcatheter aortic valve implantation (TAVI)

Comparator

Balloon-expandable TAVI

Outcome

Improvement in ejection fraction, haemodynamics, and clinical outcomes

Both balloon-expandable and self-expandable TAVI provide sustained LVEF improvement in patients with LV dysfunction, with self-expandable valves offering better haemodynamics but similar clinical outcomes.

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

In patients with reduced LVEF, TAVI produced sustained improvement in ejection fraction irrespective of valve platform, and SEV conferred a haemodynamic advantage without differences in ejection fraction or clinical outcomes.

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Balloon Versus Self‐Expandable TAVI in Patients With Left Ventricular Dysfunction: A Real‐World Comparative Study

Key Result

Key Points

Structured PICO

Main Result

Abstract

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