Deep excitation afterglow luminescent probes for biomedical applications

Yiqian Hao; Yuxia Liu; Xia Liu; Siyue Ma; D. Y. Wang; Qing Miao; Linlin Wang; Pu Chen; Dongliang Su; Jonathan L. Sessler; Bo Tang; Tony D. James; Guang Chen

doi:10.1039/d5sc09312k

January 1, 2026Chemical ScienceOpen Access

Deep excitation afterglow luminescent probes for biomedical applications

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Key Points

The central aim is to explore deep afterglow luminescent probes for their effectiveness in biomedical imaging applications.
Utilized near-infrared (NIR) light, X-ray, and ultrasound for excitation.
Evaluated imaging sensitivity and signal-to-background ratio.
Conducted comparisons against autofluorescence levels.
Achieved continuous luminescence using deep excitation methods.
Observed significant improvement in imaging sensitivity.
Documented an enhanced signal-to-background ratio compared to traditional imaging methods.

Implication

Demonstrates improved imaging sensitivity in biomedical applications, suggesting greater accuracy in diagnostics.

Abstract

Afterglow imaging provides continuous deep luminescence when excited by NIR-light, X-ray or ultrasound. Avoiding autofluorescence, improving imaging sensitivity and signal-to-background ratio.

Discussion

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Cite This Study

Hao et al. (2026) studied this question.

synapsesocial.com/papers/69b3acd302a1e69014ccee15 https://doi.org/10.1039/d5sc09312k

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Deep excitation afterglow luminescent probes for biomedical applications

Key Points

Implication

Abstract

Discussion

Cite This Study

Deep excitation afterglow luminescent probes for biomedical applications

Key Points

Implication

Abstract

Discussion

Cite This Study

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