Prospective interventional study shows improved body composition and psychosocial well-being in transmen undergoing testosterone therapy, indicating positive health impacts.
Key Points
This research aims to evaluate how testosterone gender-affirming hormonal therapy affects body composition and psychosocial well-being in transmen.
Prospective interventional study conducted over two years in a transgender clinic
Measurements included body mass index, waist-hip ratio, grip strength, serum testosterone and estradiol levels
Body composition assessed by dual energy x-ray absorptiometry
Psychosocial aspects measured with the GPSQ scale and RAND SF-36 at baseline and one year after therapy
After one year of therapy, significant increases in BMI, grip strength, and lean body mass were observed
Reduction in total fat mass and gynoid fat was significant
Improvement in GPSQ scores and quality of life was noted at the end of the study
Correlation found between waist-hip ratio and android fat distribution