c-Myc regulated long noncoding RNA TRD-AS1 to affect the progression of oral squamous cell carcinoma

Ziyue Feng; Yi Han; Xiaofeng Qin; Miaoting Fu; Xiangyang Li; Youming Zhu

doi:10.1007/s13258-026-01745-z

March 10, 2026Genes & GenomicsOpen Access

c-Myc regulated long noncoding RNA TRD-AS1 to affect the progression of oral squamous cell carcinoma

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Key Points

The study aims to explore how c-Myc regulates the long noncoding RNA TRD-AS1 and its impact on oral squamous cell carcinoma (OSCC).
Examined the regulation of TRD-AS1 by c-Myc in OSCC cells.
Assessed the effects of TRD-AS1 on cell migration and proliferation.
Analyzed changes in tumor metabolism associated with TRD-AS1 expression.
TRD-AS1 expression was positively regulated by c-Myc.
Enhanced TRD-AS1 levels correlated with increased OSCC cell migration and proliferation.
TRD-AS1 influenced tumor metabolism, particularly acid metabolism.

Implication

This research examines c-Myc's role in affecting OSCC progression through TRD-AS1, suggesting therapeutic implications.

Abstract

c-Myc positively regulated LNC TRD-AS1 in OSCC. LNC TRD-AS1 affected the migration, proliferation and metabolism of OSCC by affecting the tumor acid metabolism.

Discussion

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Cite This Study

Feng et al. (2026) studied this question.

synapsesocial.com/papers/69b3ad0502a1e69014ccf379 https://doi.org/10.1007/s13258-026-01745-z

View Full Paper

Ask AI

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c-Myc regulated long noncoding RNA TRD-AS1 to affect the progression of oral squamous cell carcinoma

Key Points

Implication

Abstract

Discussion

Cite This Study

c-Myc regulated long noncoding RNA TRD-AS1 to affect the progression of oral squamous cell carcinoma

Key Points

Implication

Abstract

Discussion

Cite This Study

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