Efficient synthesis of planar chiral diallylic 9-membered amides having a variety of substituents and stereochemical analysis thereof

Key Points

• To synthesize and analyze the stereochemical properties of 9-membered amides with various substituents.
• Synthesis of C3- and C4-substituted diallylic 9-membered amides through coupling reactions.
• Formation of iodinated intermediates from 7-membered hemiaminals.
• Analysis of dynamic chirality and stereochemical stability.
• Successful synthesis of a variety of diallylic 9-membered amides.
• Demonstrated presence of dynamic chirality and stereochemical stability in the synthesized amides.