Long-term outcomes of patients implanted with a HeartMate 3 left ventricular assist device – a real-world, single center, observational study

Stijn Legtenberg; Jozine M. ter Maaten; Michiel E. Erasmus; Michiel Kuijpers; Yvonne L. Douglas; R.A.D.A Puspitarani; Joep M. Droogh; Eva de Felice; Stan A.J. van den Broek; Jan A. Krikken; A A Voors; Kevin Damman

doi:10.1093/eschf/xvag074

March 10, 2026ESC Heart FailureOpen Access

Long-term outcomes of patients implanted with a HeartMate 3 left ventricular assist device – a real-world, single center, observational study

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Key Points

To assess long-term outcomes in patients supported by the HeartMate 3 LVAD.
Single-center observational study
Analysis of patient survival and adverse events over five years
Evaluation of clinical complications including infections and hospitalizations
Long-term survival on HeartMate 3 LVAD support exceeded 60% at 5 years
Low incidence of thrombotic complications
Continued clinical challenges from device related infections and heart failure hospitalizations

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Implication

Observational study shows low thrombotic complications and high survival on left ventricular assist device support, indicating good clinical outcomes.

Abstract

Long-term survival on HeartMate 3 LVAD support exceeded 60% at 5 years in this single-center cohort. While adverse events such as device related infections and heart failure hospitalizations continue to pose a substantial clinical challenge, the incidence of thrombotic complications was low, underscoring improvement in clinical outcomes with current generation centrifugal LVAD devices.

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Legtenberg et al. (2026) studied this question.

synapsesocial.com/papers/69b4ad9a18185d8a39801102 https://doi.org/10.1093/eschf/xvag074

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Long-term outcomes of patients implanted with a HeartMate 3 left ventricular assist device – a real-world, single center, observational study

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Long-term outcomes of patients implanted with a HeartMate 3 left ventricular assist device – a real-world, single center, observational study

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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