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A prospective observational study highlights that kidney transplant recipients have a 13.6% incidence of latent tuberculosis, emphasizing the need for ongoing surveillance.
This study recruited the largest cohort to date to follow up LTBI status in patients with kidney transplant and shows its high incidence (13.6% within 2 years) even after initial negative QFT screening. Low lymphocyte percentage and high initial QFT response are significantly correlated with incident LTBI. Both the rifamycin-containing regimen and isoniazid regimen are well tolerated in KTRs. LTBI surveillance is also recommended in post-transplant status, though a validation study is required.
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Shu et al. (2026) studied this question.
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