To examine the relationship between endotypic traits and the severity of obstructive sleep apnea.
Analysis of arousal threshold in relation to hypoxic burden and AHI
Evaluation of the nonlinear association of arousal threshold with OSA severity
Higher arousal threshold is associated with a more severe hypoxic burden
Nonlinear relationship observed between arousal threshold and AHI
Abstract
A higher arousal threshold predicted a more severe hypoxic burden but showed a nonlinear association with AHI. Arousal threshold and compensation should be considered together when evaluating OSA severity.