What question did this study set out to answer?

To evaluate urinary levels of prostaglandin D2 and compare measurement methods in airway disease contexts.

Monitoring PGD ₂ production in airway disease

View Full Paper

Ask AI

Bookmark

Authors

Evaluation of urinary levels of prostaglandin D2 in asthma indicates its potential in monitoring airway disease.

To evaluate urinary levels of prostaglandin D2 and compare measurement methods in airway disease contexts.
Collected urinary samples from patients with asthma, mastocytosis, and those undergoing bronchoprovocation.
Measured 9α,11β-PGF 2 and PGDM using enzyme immune assay and LC-MS/MS.
Conducted analysis during bronchoprovocation and aspirin challenge.
Significant increase in urinary 9α,11β-PGF 2 during allergen challenges (p=0.002).
Bland-Altman analysis indicated agreement between measurement methods for PGDM.
Mean urinary PGDM levels showed no significant change after challenges while 9α,11β-PGF 2 levels did.

Larsson et al. (2011) studied this question.

View Full Paper

Ask AI

Bookmark