Research reveals redox homeostasis affects aging in D. melanogaster, suggesting agarose oligosaccharides might improve intestinal health.
The homeostasis of ISC in aging D. melanogaster is balanced by AOS via the acetic acid-JAK/STAT axis mediated by Acetobacter persici. This axis counters age-related ISC dysregulation by balancing proliferative signals with redox homeostasis, positioning AOS as a microbiota-targeted intervention for age-associated intestinal decline.
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Fan et al. (2026) studied this question.
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