Observations reveal ionized hypercalcemia in dogs with chronic dermatopathy, suggesting calcitriol testing is essential for diagnosis.
Ionized hypercalcemia apparently mediated by excessive extrarenal calcitriol production can be seen in dogs with granulomatous skin disease. Calcitriol measurement should be included with other calcium-related testing in the workup of unexplained hypercalcemia with concurrent chronic skin disease.
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Brudvig et al. (2026) studied this question.
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