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Silver-catalyzed Regioselective Direct Dichlorotrifluoromethoxylation of Terminal Alkynes | Synapse

March 14, 2026Organic Chemistry Frontiers0 citations

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Silver-catalyzed Regioselective Direct Dichlorotrifluoromethoxylation of Terminal Alkynes

MAMuhammad B Altaf QHQingyun HuangNankai University PTPingping TangNankai University

Key Points

To investigate the regioselective direct dichlorotrifluoromethoxylation of terminal alkynes using silver catalysts.
Utilized silver-catalyzed reactions
Focused on terminal alkynes
Explored dichlorotrifluoromethoxylation techniques
Achieved regioselective incorporation of trifluoromethoxy group
Demonstrated synthetic utility of halo-trifluoromethoxylated compounds

Abstract

The incorporation of the trifluoromethoxy (OCF₃) group into alkynes remains a topic of ongoing interest in modern organic chemistry. In particular, halo-trifluoromethoxylated alkenes have significant synthetic utility, yet access to...

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Cite This Study

Altaf et al. (Thu,) studied this question.

synapsesocial.com/papers/69b4ba2718185d8a39802d05 https://doi.org/https://doi.org/10.1039/d6qo00025h