What type of study is this?

This is a Systematic Review study.

March 14, 2026Human Psychopharmacology Clinical and Experimental0 citations

Clinical Potential of Mirtazapine in Anxiety and Trauma‐Related Disorders: A Systematic Review and Meta‐Analysis of Current Evidence

CCClaudio CaiazzaRegione Campania VRVito RagoRegione Campania NSNiccolò SoliniRegione Campania

Key Points

This research evaluates the clinical potential of mirtazapine in anxiety and trauma-related disorders.
Systematic review and meta-analysis of current evidence
Comparison of mirtazapine with SSRIs in treating anxiety disorders
Assessment of mirtazapine's role in GAD and PTSD
Analysis of tolerance and side effects of mirtazapine.
Mirtazapine showed greater efficacy than SSRIs for anxiety in MDD
Considered as an alternative for first-line treatment in GAD
Mirtazapine may be beneficial as an augmentation strategy in PTSD
Generally well tolerated with potential benefits for those experiencing sleep disturbances.

Abstract

Mirtazapine was more effective than SSRIs for anxiety in MDD and may be preferred when anxiety is relevant. In GAD, mirtazapine may serve as an alternative to first-line agents, and further regulatory explorations are warranted. In PTSD, mirtazapine has potential as an augmentation strategy. Mirtazapine was generally well tolerated and may be advantageous for patients requiring rapid effect or relief from sleep disturbances.

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Cite This Study

Caiazza et al. (Sun,) studied this question.

synapsesocial.com/papers/69b4ba3618185d8a398030d7 https://doi.org/https://doi.org/10.1002/hup.70037

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