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March 1, 2026HLA

The Novel Allele, HLA‐DPA1*01:213 , With a Non‐Synonymous Mutation in Exon 3

Diamanto Kouniaki Theofilos Athanassiades Christina Salamaliki A. Tsirogianni

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Key Points

The research aims to characterize the novel HLA-DPA1*01:213 allele and its mutation.
Identified HLA-DPA1*01:213 allele
Analyzed the specific nucleotide substitution
Examined the impact of the mutation in exon 3
HLA-DPA1*01:213 allele contains a unique nucleotide substitution
The mutation occurs at codon 163
Substitution changes threonine to arginine (TGC to CGC)

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Implication

Uncovers a non-synonymous mutation in the HLA-DPA1 allele, suggesting implications for molecular genetics.

Abstract

The HLA-DPA1*01:213 allele contains a single nucleotide substitution in codon 163 (TGC to CGC).

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Cite This Study

Kouniaki et al. (2026) studied this question.

synapsesocial.com/papers/69b4fa9ab39f7826a300b45d https://doi.org/10.1111/tan.70659

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1The Novel Allele, <i>HLA‐DQA1*03:80</i>, With a Non‐Synonymous Mutation in Exon 32025 · 4 citations
2Identification of the novel <scp><i>HLA‐DPA1*01:195</i></scp> allele by next‐generation sequencing2024 · 3 citations
3Confirmation of the <i>HLA‐DPA1*01:03:35</i> Allele by Next‐Generation SequencingOriginal Research · 2026 · 1 citations
4The Novel <scp>HLA</scp> Class <scp>II</scp> Allele, <i>HLA‐DPA1*02:167</i> , Identified by <scp>PacBio</scp> SequencingOriginal Research · 2026 · 2 citations
5Characterisation of the Novel <i>HLA‐DPA1*03:25</i> Allele by Next Generation SequencingOriginal Research · 2026 · 1 citations

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Characterisation of the novel <i>HLA‐DPA1*01:12:03</i> allele by sequencing‐based typing2024
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Identification of a Novel <scp>HLA</scp> ‐ <scp>DPA1</scp> Allele With a New Amino Acid Residue in the Core Domain, <i>HLA‐DPA1*01:249</i>2026

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