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Secondary analysis reports the prognostic value of p27 post-radiotherapy in prostate cancer, suggesting implications for treatment decisions.
BACKGROUND:The cyclin-dependent kinase inhibitor p27 is a well-profiled modulator of cell cycle progression.Low nuclear p27 levels have been demonstrated to have a negative prognostic impact on outcomes in patients undergoing prostatectomy.The prognostic value of p27 after radiotherapy (RT) for prostate cancer is unknown.
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Patel et al. (2026) studied this question.
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