Introduction: Major complications (MC) in liver transplantation (LT) are common and can lead to severe consequences for both patient and graft survival.Effectively managing MC may be more beneficial than simply reducing its overall frequency.A new management metric, known as "failure to rescue" (FTR), is defined as the percentage of patients who die after experiencing MC.FTR serves as an indicator of the ability to save a patient with MC from death.There is limited literature on FTR in the context of LT.In this study, the FTR of patients treated in the LT unit is analyzed, and factors related to FTR are examined.Methods: This was a retrospective study of LT cases conducted between September 2012 and December 2021, examining preoperative, intraoperative, and postoperative variables, as well as postoperative complications and length of stay.FTR was defined as the number of patients who died after experiencing MC (Clavien-Dindo grade III) divided by the total number of patients with MC.Results: 321 patients were included, of whom 123 (38.3%) experienced MC.The FTR was 25.2%.This rate was higher among patients with elevated MELD scores J o u r n a l P r e -p r o o f and among those with non-biliary complications.Multivariate regression revealed that only non-biliary complications were statistically significant.Conclusion: FTR was 25.2%.Patients who experienced FTR were identified as a subgroup with higher MELD scores and complications other than biliary.
Ramia et al. (Sun,) studied this question.
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