Severe bleeding diathesis after dental extractions: a complex case of coagulation disturbances in a patient with multiple myeloma

Q: What does this research mean for the field?

Low-dose tranexamic acid effectively controls hemorrhage and improves healing in a patient with multiple myeloma and severe bleeding diathesis after dental extraction. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

Fernanda de Paula Eduardo; Letícia Mello Bezinelli; Vitor Abreu de Goes; Mariana Henriques Ferreira; Marcella Ferreira Gobbi; Lívia Goron Bergamin; José Mauro Kutner; Luciana Corrêa; José Luiz Bonamigo Filho

doi:10.31744/einstein_journal/2026rc1902

January 1, 2026Einstein (São Paulo)Open Access

Severe bleeding diathesis after dental extractions: a complex case of coagulation disturbances in a patient with multiple myeloma

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Key Points

To investigate the coagulation disturbances leading to severe bleeding after dental extractions in a patient with multiple myeloma.
Case report detailing a male patient with multiple myeloma.
Laboratory tests assessed coagulation factors, including prothrombin and thrombin times.
Initial treatment involved intravenous vitamin K and fresh frozen plasma, followed by low-dose tranexamic acid.
Laboratory tests showed prolonged prothrombin and thrombin times and reduced factor VII levels.
Initial management failed to achieve hemostasis, highlighting the complexity of the coagulation disturbance.
Tranexamic acid successfully controlled hemorrhage and improved healing of the dental sockets.

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Implication

Case report reveals effective hemorrhage control in a patient with multiple myeloma using tranexamic acid, suggesting treatment pathways for similar cases.

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Cite This Study

Eduardo et al. (2026) studied this question.

synapsesocial.com/papers/69b4fbc1b39f7826a300c21e https://doi.org/10.31744/einstein_journal/2026rc1902

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Severe bleeding diathesis after dental extractions: a complex case of coagulation disturbances in a patient with multiple myeloma

Key Points

No abstract yet

Implication

Discussion

Cite This Study

Severe bleeding diathesis after dental extractions: a complex case of coagulation disturbances in a patient with multiple myeloma

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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