What question did this study set out to answer?

The study aims to evaluate factors contributing to adverse effects following snake antivenom treatment, with a focus on pharmacological interventions.

March 14, 2026ToxinsOpen Access

Pharmacological Treatments and Adverse Reactions Following Snake Antivenom Therapy: A Collaborative Study by Healthcare Professionals in the Southernmost Region of Thailand

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The study aims to evaluate factors contributing to adverse effects following snake antivenom treatment, with a focus on pharmacological interventions.
Conducted a retrospective analysis of 980 confirmed snakebite patients from 2016 to 2021.
Evaluated adverse reactions post-antivenom administration in treated patients.
Performed univariate and multivariate analyses to assess correlations with medications.
Calculated prevalence rates and 95% confidence intervals for observed reactions.
86.7% of patients exhibited no adverse reactions following antivenom administration.
13.3% experienced reactions, including skin rash, itching, and wheezing.
Adverse reactions were notably higher among patients referred for treatment (11.7%).
Epinephrine and antihistamines effectively mitigated hypersensitivity reactions.
Tramadol and antihistamines significantly reduced adverse reactions after antivenom use.

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Implication

Retrospective study examines adverse reactions in snakebite victims, suggesting improved antivenom care approaches.

Cite This Study

Promsorn et al. (2026) studied this question.

synapsesocial.com/papers/69b4fbd5b39f7826a300c40c https://doi.org/10.3390/toxins18030139

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Pharmacological Treatments and Adverse Reactions Following Snake Antivenom Therapy: A Collaborative Study by Healthcare Professionals in the Southernmost Region of Thailand

Key Points

Discussion

Implication

Cite This Study

Pharmacological Treatments and Adverse Reactions Following Snake Antivenom Therapy: A Collaborative Study by Healthcare Professionals in the Southernmost Region of Thailand

Key Points

Discussion

Implication

Cite This Study

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