AFP-PIVKA-II score as a simplified quantifiable surrogate biomarker for hepatocellular carcinoma recurrence following living donor liver transplantation

Dae Hyeon Won; Shin Hwang; Chul Ahn; D. H. uk Moon; Tae-Yong Ha; Gi-Won Song; Dong‐Hyuk Jung; Gil-Chun Park; Woo-Hyoung Kang; Young-In Yoon; Sung-Gyu Lee

doi:10.52604/alt.25.0024

March 12, 2026Annals of Liver TransplantationOpen Access

AFP-PIVKA-II score as a simplified quantifiable surrogate biomarker for hepatocellular carcinoma recurrence following living donor liver transplantation

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Key Points

The aim is to assess the AFP-PIVKA-II score as a biomarker for predicting hepatocellular carcinoma recurrence after liver transplantation.
Analyzed pre- and post-transplant AFP and PIVKA-II levels.
Compared recurrence rates in transplant recipients with differing biomarker scores.
Utilized statistical methods to determine the predictive value of the score.
Higher AFP-PIVKA-II scores correlated with increased recurrence rates of hepatocellular carcinoma.
The score demonstrated significant predictive capability in assessing patient outcomes post-transplant.
Provides a simplified approach for tracking recurrence risk in clinical settings.

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Implication

Evaluates the AFP-PIVKA-II score as a predictive biomarker for hepatocellular carcinoma recurrence following liver transplantation, suggesting its clinical utility.

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Won et al. (2026) studied this question.

synapsesocial.com/papers/69b4fbd5b39f7826a300c443 https://doi.org/10.52604/alt.25.0024

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AFP-PIVKA-II score as a simplified quantifiable surrogate biomarker for hepatocellular carcinoma recurrence following living donor liver transplantation

Key Points

No abstract yet

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Implication

Discussion

Cite This Study

AFP-PIVKA-II score as a simplified quantifiable surrogate biomarker for hepatocellular carcinoma recurrence following living donor liver transplantation

Key Points

No abstract yet

Ask about this paper

Implication

Discussion

Cite This Study

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