A microfluidic method for controlled generation and trapping of membraneless water-in-water droplets

Chi Li; Hailin Fu; Kalpit Bakal; Jaap den Toonder; E. W. Meijer; Sailing He; Hans M. Wyss

doi:10.1039/d5lc01055a

January 1, 2026Lab on a ChipOpen Access

A microfluidic method for controlled generation and trapping of membraneless water-in-water droplets

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Key Points

This research aims to develop a microfluidic method for creating and trapping membraneless droplets in aqueous environments.
Utilized microfluidic devices to manipulate flow and geometry.
Created aqueous two-phase systems to stabilize droplets.
Measured droplet formation and trapping efficiency.
Successfully generated membraneless droplets with high precision.
Demonstrated ability to control droplet size and trapping duration.
Findings indicate potential for new applications in biochemical studies.

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Implication

Microfluidic devices demonstrate controlled generation of membraneless droplets in aqueous two-phase systems, suggesting new applications.

Abstract

Aqueous two-phase systems (ATPS) provide a versatile platform for controlling microscale aqueous environments. Microfluidic devices are particularly valuable for studying such systems, as they allow precise control of geometry, flow,...

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Cite This Study

Li et al. (2026) studied this question.

synapsesocial.com/papers/69b4fbf9b39f7826a300c89f https://doi.org/10.1039/d5lc01055a

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A microfluidic method for controlled generation and trapping of membraneless water-in-water droplets

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

A microfluidic method for controlled generation and trapping of membraneless water-in-water droplets

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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