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The study aims to investigate the evolutionary and geographic dynamics of Nipah virus strains in Bangladesh to enhance outbreak management.

March 14, 2026Microbiology SpectrumOpen Access

Mapping the geodispersal and evolutionary dynamics of regional Nipah virus strain in Bangladesh

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The study aims to investigate the evolutionary and geographic dynamics of Nipah virus strains in Bangladesh to enhance outbreak management.
Conducted phylodynamic and geographic analyses using nucleoprotein gene sequences from human and bat samples.
Incorporated publicly available NiV genomes up through November 2024.
Applied Bayesian evolutionary analysis to spatiotemporal data of the virus.
Identified two major lineages of Bangladeshi NiV: BD-1 and BD-2, with the latter containing most bat-derived sequences as of 2023.
Estimated evolutionary rate of NiV in Bangladesh at 4.89 × 10⁻⁴ substitutions/site/year.
Revealed geographic clusters of NiV strains ranging from 6.54 km to 116.09 km, indicating ongoing evolution and expansion.

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Analyzes the geodispersal and phylodynamics of Nipah virus in Bangladesh, highlighting key risk areas.

Rahman et al. (2026) studied this question.

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