Key result
Global age-standardized IHD prevalence, incidence, and mortality decline across all age groups from 1990 to 2021.
While the absolute number of global IHD cases has increased from 1990 to 2021, age-standardized rates of incidence and mortality have declined, highlighting the need for region-specific prevention strategies.
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Current IHD prevention remains effective; confirms global progress while extending need for region-specific strategies.
From 1990 to 2021, the global absolute number of IHD cases increased, yet ASRs for prevalence, incidence, DALYs, and mortality declined across all age groups and genders, with greater reductions observed in higher SDI regions. Projections indicate a continued decrease in ASIR through 2030, with the most significant reductions expected in the ≥70 years age group. These findings highlight the critical need for enhanced prevention and healthcare policies to address the global IHD burden effectively. In low- and middle-SDI regions, policy efforts should be intensified to control risk factors, whereas in high-SDI regions the focus should be on secondary prevention and rehabilitation.
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Jing et al. (2026) studied this question. From 1990 to 2021, the age-standardized rates for ischemic heart disease prevalence, incidence, and mortality declined across all age groups globally.
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