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December 14, 2022European Heart Journal SupplementsOpen Access

226 Echocardiographic and Invasive Evaluation of Left Atrial Pressure in Patients Undergoing Catheter Ablation for Atrial Fibrillation

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Why the study?

Estimation of LV filling pressure provides important clinical information, but challenges in measuring it invasively make it difficult to use routinely.

Do novel echocardiographic measures of cardiac structure and function accurately predict invasive left atrial pressure in patients undergoing catheter ablation for atrial fibrillation?

Population

73 patients undergoing primary catheter ablation for AF

Comparison

TTE measures of cardiac structure and function vs invasive LAP

Design

Multicenter prospective study

Authors

ABAndrea BonelliRIRiccardo M. InciardiACAngelica Cersosimo

Discussion

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Overview

May aid non-invasive LAP estimation in AF; leaves open prospective validation before clinical adoption.

Structured PICO

Do novel echocardiographic measures of cardiac structure and function accurately predict invasive left atrial pressure in patients undergoing catheter ablation for atrial fibrillation?

P
Population
73 patients undergoing primary catheter ablation for atrial fibrillation, mean age 65 ± 8, 27% female.
I
Intervention
Transthoracic echocardiography (TTE) assessing measures of left ventricle (LV), left atrial (LA), and right ventricle (RV) structure and function, including speckle tracking echocardiography.
C
Comparator
Invasive measurement of left atrial pressure (LAP) during atrial fibrillation ablative procedure.
O
Outcome
Association between echocardiographic measures of cardiac structure and function and invasive left atrial pressure (LAP), and diagnostic accuracy to predict elevated LAP (≥ 15mmHg).surrogate

Novel echocardiographic measures, specifically left atrial minimal volume and emptying fraction, provide reliable non-invasive estimates of elevated left atrial pressure in patients with atrial fibrillation.

Cite This Study

Bonelli et al. (2022) studied this question.

synapsesocial.com/papers/69b50976dd00f7596dbabc42https://doi.org/10.1093/eurheartjsupp/suac121.049
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Increased left atrial pressure is associated with fibrosis, elevated mechanical load and ventricular diastolic dysfunction in patients undergoing AF catheter ablation2024
  2. 2Left atrial strain parameters to predicting elevated left atrial pressure in patients with atrial fibrillation2024 · 4 citations
  3. 3Measurement of Left Atrial Pressure is a Good Predictor of Freedom From Atrial Fibrillation2014 · 15 citations
  4. 4Left atrial strain parameters to predicting elevated left atrial pressure in patients with atrial fibrillation2024 · 1 citations
  5. 5Combined E velocity and E/e’ as an estimate of elevated left atrial pressure in patients with atrial fibrillation2022